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A meta-analysis of the comparison of phlebitis between midline catheters and peripherally inserted central catheters

Huapeng Lu1, Qinling Yang1, Boyan Tian1

  • 1Department of Hepatobiliary and Pancreas Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.

International Journal of Nursing Practice
|June 2, 2021
PubMed
Abstract

Insights

Midline catheters and peripherally inserted central catheters show no significant difference in phlebitis risk. This meta-analysis of seven studies found similar phlebitis incidence, aiding vascular access device selection.

Area of Science:

  • Medical Devices
  • Vascular Access
  • Infection Control

Background:

  • Phlebitis is a common complication of vascular access devices.
  • Midline catheters and peripherally inserted central catheters are frequently used for infusion therapy.
  • Comparing the risk of phlebitis between these devices is crucial for patient safety and optimal device selection.

Purpose of the Study:

  • To conduct a meta-analysis comparing the risk of phlebitis between midline catheters and peripherally inserted central catheters.
  • To systematically assess the available evidence on phlebitis incidence associated with these two types of vascular access devices.

Main Methods:

  • Systematic literature review and meta-analysis.
  • Searched multiple databases (Web of Science, PubMed, Scopus, etc.) from inception to May 2020.
  • Included seven studies with 1377 participants; assessed publication bias using RevMan 5.3.

Main Results:

  • The incidence of phlebitis was 1.52% for midline catheters and 3.41% for peripherally inserted central catheters.
  • Meta-analysis revealed no statistically significant difference in phlebitis risk between the two device types.
  • Sensitivity analysis indicated fair overall study results, with no significant publication bias detected.

Conclusions:

  • This meta-analysis indicates that midline catheters and peripherally inserted central catheters have comparable risks of phlebitis.
  • The findings suggest that factors beyond phlebitis risk should be considered when choosing between these vascular access devices.
  • This study offers the first systematic assessment comparing phlebitis risk between midline and peripherally inserted central catheters.
Keywords:
infusion therapymeta-analysismidline catheternursingperipherally inserted central catheterphlebitis

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