Scurvy and Tinea Corporis Simulating Leukocytoclastic Vasculitis

Area of Science:

• Dermatology
• Pathology
• Rheumatology

Background:

• Leukocytoclastic vasculitis (LCV) is a small vessel inflammatory condition often linked to immune complexes, infections, medications, or systemic diseases.
• Determining the etiology and extent of LCV is crucial for timely intervention and effective management.

Observation:

• This report details cases where scurvy and tinea corporis exhibited histopathologic features consistent with LCV.
• Patients with these conditions showed marked clinical improvement upon treatment of the underlying scurvy or tinea corporis.

Findings:

• Histopathologic findings of early or evolving LCV can manifest in conditions beyond typical triggers, such as scurvy and tinea corporis.
• The study identifies scurvy and tinea corporis as potential, less commonly recognized, causes presenting with LCV histopathology.

Implications:

• These findings underscore the necessity of considering a broader differential diagnosis for LCV, including nutritional deficiencies and fungal infections.
• Prompt identification and treatment of the underlying cause, like scurvy or tinea corporis, are vital for successful LCV patient management and improved outcomes.