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Updated: Nov 2, 2025
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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
3-Aminooxetanes: versatile 1,3-amphoteric molecules for intermolecular annulation reactions
Zengwei Lai1,2, Renwei Zhang1, Qiang Feng1
1Department of Chemistry, Shenzhen Research Institute, The Hong Kong University of Science and Technology Clear Water Bay Hong Kong SAR Kowloon China sunjw@ust.hk.
Abstract:
Despite the versatility of amphoteric molecules, stable and easily accessible ones are still limitedly known. As a result, the discovery of new amphoteric reactivity remains highly desirable. Herein we introduce 3-aminooxetanes as a new family of stable and readily available 1,3-amphoteric molecules and systematically demonstrated their amphoteric reactivity toward polarized π-systems in a diverse range of intermolecular [3 + 2] annulations. These reactions not only enrich the reactivity of oxetanes, but also provide convergent access to valuable heterocycles.
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