Related Experiment Video
Updated: Nov 2, 2025

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
Can Established Vapers Distinguish Different PG:VG Ratios? A Pilot Study.
Liane M Schneller1, Taylor S Vanderbush1, Richard J O'Connor1
1Liane M. Schneller, Pre-Doctoral Trainee, Department of Health Behavior, Division of Cancer Prevention and Population Sciences, Roswell Park Comprehensive Cancer Center, Buffalo, NY. Taylor S. Vanderbush, Laboratory Technician, Department of Health Behavior, Division of Cancer Prevention and Population Sciences, Roswell Park Comprehensive Cancer Center, Buffalo, NY. Richard J. O'Connor, Professor of Oncology, Department of Health Behavior, Division of Cancer Prevention and Population Sciences, Roswell Park Comprehensive Cancer Center, Buffalo, NY.
Established vapers struggled to differentiate e-liquid propylene glycol: vegetable glycerin (PG:VG) ratios. These findings suggest PG:VG ratios may not significantly impact the vaping sensory experience.
Area of Science:
- Vaping and E-cigarette Research
- Sensory Science
- Consumer Product Analysis
Background:
- Propylene glycol (PG) and vegetable glycerin (VG) are primary e-liquid solvents.
- The PG:VG ratio influences e-liquid viscosity, vapor production, and throat hit.
- Understanding sensory perception of PG:VG ratios is crucial for product development and regulation.
Purpose of the Study:
- To investigate if experienced vapers can discern subtle differences in PG:VG ratios.
- To assess the impact of varying PG:VG ratios on the sensory experience of e-liquids.
- To determine the salience of PG:VG ratios in e-liquid formulations.
Main Methods:
- A triangle test was employed with watermelon-flavored e-liquids at fixed nicotine (16mg/mL) and flavor levels.
- Three distinct PG:VG ratios (30:70, 50:50, 70:30) were used.
- Participants identified the 'odd' product among three samples and rated their sensory experience.
Main Results:
- Only 34.9% of participants correctly identified the 'odd' e-liquid based on PG:VG ratio differences.
- Subjective ratings for the 'odd' product were generally low.
- Aversion scores showed a significant difference based on correct identification (p = .045).
Conclusions:
- Experienced vapers could not consistently distinguish between different PG:VG ratios, even with substantial variations.
- Correct identification of PG:VG ratios did not consistently correlate with subjective sensory ratings.
- Preliminary evidence suggests PG:VG ratio may not be a primary driver of sensory perception in vaping.
More Related Videos
08:33Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies
Published on: April 12, 2022
09:30A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
Published on: January 18, 2018
Related Concept Videos
Distillation: Vapor–Liquid Equilibria
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...