What gastroenterologists should know about SARS-CoV 2 vaccine: World Endoscopy Organization perspective

Area of Science:

• Immunology
• Vaccinology
• Public Health

Background:

• The novel Coronavirus (SARS-CoV-2) pandemic has led to millions of deaths globally.
• Regulatory bodies like the FDA and EMA have approved initial COVID-19 vaccines, with more anticipated.
• Diverse vaccine development strategies are being employed to combat the virus.

Purpose of the Study:

• To provide a comprehensive review of approved and developing COVID-19 vaccines.
• To explore potential risks, benefits, and vaccination prioritization strategies.
• To equip healthcare professionals with updated information for patient counseling.

Main Methods:

• Review of traditional vaccine approaches (inactivated virus, protein subunit, recombinant virus).
• Analysis of innovative strategies including viral vector, RNA-based, and DNA-based vaccines.
• Examination of vaccination campaigns and their implications for patient care.

Main Results:

• Gastroenterologists are key information sources for patients regarding SARS-CoV-2 vaccination.
• Vulnerable populations, including IBD, chronic liver disease, and GI cancer patients, require specific counseling.
• Vaccination campaigns commenced in late 2020 in the US and Europe.

Conclusions:

• Healthcare providers must be well-informed to counsel patients on COVID-19 vaccines.
• A thorough understanding of vaccine risks, benefits, and prioritization is crucial.
• This review aims to support evidence-based vaccination guidance for diverse patient groups.