Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Trihybrid Crosses02:27

Trihybrid Crosses

24.5K
Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal...
24.5K
Dihybrid Crosses01:18

Dihybrid Crosses

78.3K
Overview
78.3K
Seed Structure and Early Development of the Sporophyte02:33

Seed Structure and Early Development of the Sporophyte

29.9K
Seed structures are composed of a protective seed coat surrounding a plant embryo, and a food store for the developing embryo. The embryo contains the precursor tissues for leaves, stem, and roots. The endosperm and cotyledons—seed leaves—act as the food reserves for the growing embryo.
29.9K
Monohybrid Crosses01:20

Monohybrid Crosses

234.8K
Overview
234.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ankh-Score Produces Better Sequence Alignments Than AlphaFold3.

Proteins·2026
Same author

Protein embeddings and local alignments.

Computational and structural biotechnology journal·2026
Same author

Component puzzle protein-protein interaction prediction.

Briefings in bioinformatics·2025
Same author

Explainability of Protein Deep Learning Models.

International journal of molecular sciences·2025
Same author

Isolation, structural characterization of (1 → 4), (1 → 6)-α-D-glucan from Dioscorea Alata and synthesis and catalytic activity studies of (1 → 4), (1 → 6)-α-D-glucan derived carbon dots.

Carbohydrate research·2025
Same author

Scoring alignments by embedding vector similarity.

Briefings in bioinformatics·2024

Related Experiment Video

Updated: Nov 2, 2025

Reliable Method for Assessing Seed Germination, Dormancy, and Mortality under Field Conditions
07:03

Reliable Method for Assessing Seed Germination, Dormancy, and Mortality under Field Conditions

Published on: November 6, 2016

10.7K

ALeS: adaptive-length spaced-seed design.

Arnab Mallik1, Lucian Ilie1

  • 1Department of Computer Science, University of Western Ontario, London, ON N6A 5B7, Canada.

Bioinformatics (Oxford, England)
|June 9, 2021
PubMed
Summary

We developed ALeS, a new algorithm for designing highly sensitive spaced seeds used in biological sequence similarity searches. ALeS outperforms existing methods and accurately estimates seed sensitivity for improved biological research.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Sequence similarity searches are fundamental in biological research, with tools like BLAST widely employed.
  • The efficiency of BLAST relies on identifying 'seeds,' and using multiple spaced seeds offers significant improvement potential.
  • Designing optimal spaced seeds is computationally challenging, necessitating advanced heuristic algorithms.

Purpose of the Study:

  • To introduce a novel algorithm and software, ALeS, for designing highly sensitive spaced seeds.
  • To provide a method for accurately estimating the sensitivity of any given seed.
  • To improve upon the state-of-the-art in spaced seed design for biological sequence analysis.

Main Methods:

  • Development of the ALeS algorithm for spaced seed design.

More Related Videos

Scalable, Flexible, and Cost-Effective Seedling Grafting
09:33

Scalable, Flexible, and Cost-Effective Seedling Grafting

Published on: January 6, 2023

2.1K
A Simple Protocol for Mapping the Plant Root System Architecture Traits
11:09

A Simple Protocol for Mapping the Plant Root System Architecture Traits

Published on: February 10, 2023

3.3K

Related Experiment Videos

Last Updated: Nov 2, 2025

Reliable Method for Assessing Seed Germination, Dormancy, and Mortality under Field Conditions
07:03

Reliable Method for Assessing Seed Germination, Dormancy, and Mortality under Field Conditions

Published on: November 6, 2016

10.7K
Scalable, Flexible, and Cost-Effective Seedling Grafting
09:33

Scalable, Flexible, and Cost-Effective Seedling Grafting

Published on: January 6, 2023

2.1K
A Simple Protocol for Mapping the Plant Root System Architecture Traits
11:09

A Simple Protocol for Mapping the Plant Root System Architecture Traits

Published on: February 10, 2023

3.3K
  • Extensive testing and comparison of ALeS against existing state-of-the-art programs.
  • Implementation of a method for accurate sensitivity estimation of arbitrary seeds.

    • Main Results:

    • ALeS generates more sensitive seeds compared to current leading programs.
    • The ALeS software provides accurate sensitivity estimations for various seeds.
    • Demonstrated superior performance of ALeS through comprehensive evaluations.

    Conclusions:

    • ALeS represents a significant advancement in spaced seed design for sequence similarity.
    • The ability to accurately estimate seed sensitivity facilitates better tool development.
    • ALeS offers improved sensitivity for biological sequence analysis, enhancing research capabilities.