Stay-at-home orders associate with subsequent decreases in COVID-19 cases and fatalities in the United States

James H Fowler1,2, Seth J Hill2, Remy Levin3

  • 1Infectious Diseases and Global Public Health Division, University of California, San Diego, San Diego, CA, United States of America.

Plos One
|June 10, 2021
PubMed

Insights

Stay-at-home orders significantly reduced COVID-19 cases and fatalities in the US. These public health interventions led to substantial decreases in weekly cases and deaths within three weeks of implementation.

Area of Science:

  • Epidemiology
  • Public Health Policy
  • Biostatistics

Background:

  • Stay-at-home orders are a key non-pharmaceutical intervention to control infectious disease spread.
  • The effectiveness of these orders during the COVID-19 pandemic in the US, lacking national coordination, requires empirical evaluation.

Purpose of the Study:

  • To quantify the impact of stay-at-home orders on COVID-19 cases and fatalities at the county level in the United States.
  • To assess the association between the implementation of stay-at-home orders and changes in disease transmission and mortality.

Main Methods:

  • Utilized a difference-in-differences design comparing counties with and without stay-at-home orders.
  • Integrated county-level daily COVID-19 case and fatality data with the timing of stay-at-home orders for the initial seven weeks of the outbreak.
  • Controlled for unmeasured local (e.g., healthcare capacity) and temporal (e.g., national policies) confounders.

Main Results:

  • Stay-at-home orders were associated with significant reductions in weekly COVID-19 cases: 30.2% after one week, 40.0% after two weeks, and 48.6% after three weeks.
  • A 59.8% average reduction in weekly fatalities was observed three weeks after order implementation.
  • Estimated that these orders potentially averted 390,000 cases and 41,000 fatalities within three weeks in implementing localities.

Conclusions:

  • Stay-at-home orders demonstrated a significant association with reduced COVID-19 cases and fatalities in the early stages of the pandemic.
  • The findings support the utility of stay-at-home orders as an effective public health strategy for mitigating disease spread and mortality.
  • Policy implications highlight the importance of timely and geographically varied implementation of such measures.

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