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Different nutritional screening tools and recommended screening algorithm for pediatric oncology patients
Nora Gallo1, Klara Horvath1, Krisztina Czuppon1
12nd Department of Pediatrics, Semmelweis University, Budapest, 1094, 7-9 Tuzolto Street, Hungary.
Clinical Nutrition (Edinburgh, Scotland)
|June 15, 2021
Summary
The Nutrition risk screening for pediatric cancer (NRS-PC) tool better identifies low muscle mass in pediatric oncology patients than the SCAN tool. Bio-impedance analysis is crucial for low BMI patients to assess nutritional risk.
Area of Science:
- Pediatric Oncology
- Nutritional Science
- Biomarkers
Background:
- Childhood cancer impacts nutritional status, affecting disease progression and outcomes.
- Effective nutritional screening is vital for optimizing care in pediatric oncology.
- Early identification of nutritional risk can improve treatment efficacy and patient prognosis.
Purpose of the Study:
- To introduce a novel nutritional risk screening method for pediatric oncology.
- To compare the developed method against a validated tool and bio-impedance measures.
- To propose an optimized screening algorithm for clinical use in pediatric cancer facilities.
Main Methods:
- Data from 109 pediatric oncology patients (ages 3-18) were analyzed.
- Nutritional status was assessed using the Nutrition screening tool for childhood cancer (SCAN), Nutrition risk screening for pediatric cancer (NRS-PC), and bio-impedance analysis.
- Classifier properties for low muscle mass (via bio-impedance) were compared between SCAN and NRS-PC.
Main Results:
- The NRS-PC demonstrated superior classifier properties for identifying low muscle mass compared to SCAN (AUC 0.75 vs. 0.67).
- NRS-PC showed a statistically significant advantage (p=0.014) in identifying children with lower muscle mass.
- No significant differences in classification were observed across different disease phases.
Conclusions:
- The NRS-PC tool is recommended for initial screening, particularly for high BMI pediatric oncology patients.
- For patients with low BMI, bio-impedance analysis provides more accurate insights into muscle mass and nutritional risk.
- Further research is needed to confirm the sensitivity of NRS-PC in normal BMI pediatric cancer patients.
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