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Human adjuvant disease following augmentation mammoplasty
S J Brozena1, N A Fenske, C W Cruse
1Department of Internal Medicine, University of South Florida College of Medicine, Tampa 33612.
Archives of Dermatology
|September 1, 1988
Summary
Silicone breast implants can cause a systemic sclerosis-like illness, known as human adjuvant disease. Removing the implants led to significant recovery in both patients, highlighting a potential treatment.
Area of Science:
- Rheumatology
- Plastic Surgery
- Immunology
Background:
- Silicone augmentation mammoplasty is a common cosmetic procedure.
- Systemic sclerosis-like symptoms can manifest years post-implantation.
Observation:
- Two patients developed progressive, systemic sclerosis-like symptoms after silicone breast implants.
- Clinical abnormalities included features mimicking systemic sclerosis.
Findings:
- Symptom resolution occurred after the removal of silicone breast implants.
- This condition is increasingly recognized as human adjuvant disease.
Implications:
- Human adjuvant disease is a potential complication of silicone implants.
- Implant removal may be an effective treatment for human adjuvant disease.
- Further research into the immunopathogenesis of human adjuvant disease is warranted.