Related Experiment Video
Updated: Nov 1, 2025

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
New insights in treatment of monosymptomatic enuresis
Morad Bani-Hani1, Abdullah Alhouri2, Alaa Sharabi3
1Department of Urology, Faculty of Medicine, Hashemite University, Zarqa, Jordan.
Insights
Children with primary nocturnal enuresis (PNE) who maintain a regular sleep schedule are significantly more likely to experience bedwetting at a consistent time. This suggests a link between sleep regularity and enuresis timing.
Area of Science:
- Pediatrics
- Sleep Medicine
- Urology
Background:
- Primary nocturnal enuresis (PNE) is defined as uncontrollable bed-wetting in children over 5 years old.
- Sleep disturbances are common in children with PNE, potentially influencing or resulting from altered sleep structures.
Purpose of the Study:
- To investigate the relationship between sleep regularity and the timing of bedwetting episodes in children with monosymptomatic nocturnal enuresis (MNE).
Main Methods:
- A study involving 180 children aged 6-18 with MNE.
- Data collected included whether the child was a regular sleeper and a regular bed wetter.
- Study adhered to STROCCS criteria.
Main Results:
- Children aged 7-10 were more likely to wet the bed at a specific time compared to those aged 11-13 (p=0.001).
- Children with regular sleep times were 6.74 times more prone to bedwetting at a specific time (p<0.001).
Conclusions:
- Findings suggest a potential correlation between adherence to a regular sleep schedule and the timing of enuresis.
- This study is hypothesis-generating regarding the impact of sleep patterns on nocturnal enuresis timing.
Objective:
Nocturnal enuresis (NE) is defined as uncontrollable bed-wetting for at least three consecutive months in children over 5 years. Sleep could be dramatically altered in children with primary nocturnal enuresis (PNE); consequently, this helps to confirm the assumption that PNE appears to modify sleep structure, or it might be the result of an irregular sleep structure itself.
Method:
This study conducted on 180 patients with monosymptomatic nocturnal enuresis. Their age was ranged from 6 to 18 years, and they were still having nocturnal enuresis episodes. We record two main points: first, if the child is a regular sleeper or not. The second point if the child is a regular bed wetter or not. This work fully compliant with the STROCCS criteria (Agha et al., 2019).
Result:
A total of 180 children were included (Male 122, 67.8%, Female 58, 32.2%). The mean age was 8.9 (±2.4). This study showed that children aged 7-10 years are significantly more inclined to be reported as specific time bed-wetter's, whereas those aged between 11 and 13 are significantly less likely to wet their bed at a specific time (p = 0.001). Children who tend to sleep more often near a specific time each night are 6.74 times more prone to bed-wet around a particular time during their sleep (p < 0.001).
Conclusion:
This study can be considered as hypothesis-generating that shed light on the possible correlation between the adherence to sleep at a specific time and its effect on the time of enuresis and the number of bedwetting.
More Related Videos
06:46Author Spotlight: Enhanced Urodynamic Method for Precise Urine Measurement in Awake Mice with Neurogenic Bladder
Published on: June 7, 2024
10:07Cystometric and External Urethral Sphincter Measurements in Awake Rats with Implanted Catheter and Electrodes Allowing for Repeated Measurements
Published on: January 30, 2018
Related Concept Videos
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Urinary Tract Infection IV: Nursing Management
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
Urodynamic Studies: Uroflowmetry
Urine Studies II: Urine Culture and Sensitivity Test
Urinary Tract Infection II: Pathophysiology