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Updated: Nov 1, 2025

Nitropeptide Profiling and Identification Illustrated by Angiotensin II
Published on: June 16, 2019
Changes in Angiotensin Peptides in Plasma and Urine in Patients with Anaphylaxis
Abstract:
Angiotensins (ANG) I and II were measured in the plasma of patients with hymenoptera venom allergy and found to be significantly decreased as compared to controls. An inverse correlation between the plasma levels of ANG I and ANG II and the intensity of clinical symptoms of anaphylaxis was observed. In a separate study, ANG I and ANG II were measured in urine from healthy volunteers and from patients with anaphylactic reactions to drugs, food, and additives. An increase in both peptides was observed in patients with anaphylactic reactions during oral provocation. These findings suggest a possible involvement of ANG peptides in anaphylactic reactions.
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