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A Cost-Effective Analysis of the CYCLE-HD Randomized Controlled Trial
Daniel S March1,2,3, Adam W Hurt1, Charlotte E Grantham1,3
1Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
Kidney International Reports
|June 25, 2021
Summary
Intradialytic cycling (IDC) exercise during dialysis is cost-effective, reducing healthcare costs and improving quality of life. National implementation of IDC programs is recommended for end-stage kidney disease patients.
Area of Science:
- Nephrology
- Exercise Physiology
- Health Economics
Background:
- Cost-effectiveness of intradialytic cycling (IDC) during dialysis has not been formally analyzed.
- Objective: To determine the impact of a 6-month IDC program on healthcare costs.
Purpose of the Study:
- To conduct a formal cost-effectiveness analysis of intradialytic cycling (IDC) programs.
- To evaluate the effect of IDC on healthcare utilization and quality of life (QoL) in patients undergoing hemodialysis.
Main Methods:
- Retrospective cost-effectiveness analysis of adult end-stage kidney disease patients in the CYCLE-HD trial.
- Extracted data on hospitalizations, consultations, and medications for 6 months pre-, during, and post-IDC.
- Analyzed costs from a healthcare service perspective, including IDC implementation costs.
Main Results:
- A 6-month IDC program showed reduced healthcare utilization costs compared to controls.
- IDC had a 73% chance of being cost-effective at £20,000-£30,000 per QALY gained.
- Extrapolated QoL data to 12 months indicated a 93-94% probability of IDC being cost-effective.
Conclusions:
- A 6-month intradialytic cycling program is a cost-effective intervention.
- National implementation of IDC programs should be prioritized for hemodialysis patients.
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