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Related Experiment Video

Updated: Nov 1, 2025

Deep Vascular Imaging in the Eye with Flow-Enhanced Ultrasound

Deep Vascular Imaging in the Eye with Flow-Enhanced Ultrasound

Published on: October 4, 2021

Imaging the Retinal Vasculature.

Stephen A Burns¹, Ann E Elsner¹, Thomas J Gast¹

¹Indiana University School of Optometry, Bloomington, Indiana 47405, USA; email: staburns@indiana.edu, aeelsner@indiana.edu, bugbane2@gmail.com.

Annual Review of Vision Science

|June 25, 2021

Summary

This summary is machine-generated.

Advanced retinal imaging allows precise, noninvasive measurements of ocular vascular function and structure. This technology promises to revolutionize understanding and management of retinal vascular diseases.

Keywords:

adaptive optics blood flow ophthalmoscopy optical coherence tomography retina structure and function vasculature

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Published on: March 12, 2022

Area of Science:

Ophthalmology
Biomedical Engineering
Physiology

Background:

Retinal vasculature plays a crucial role in vision and is implicated in various diseases.
Noninvasive in vivo measurements of ocular vascular function are essential for research and clinical practice.

Purpose of the Study:

To provide an overview of advanced imaging and optical measurement techniques for ocular vasculature.
To discuss the physical principles governing blood flow and regulation within the eye.
To introduce retinal vascular diseases and their management.

Main Methods:

Review of current noninvasive retinal imaging technologies.
Discussion of optical measurement techniques based on reflectance and absorption.
Emphasis on contrast enhancement methods, particularly those sensitive to cell motion for perfusion and velocity measurements.

Main Results:

Advances in retinal imaging enable precise in vivo measurements of capillary blood flow, oxygen delivery, and perfused vessel mapping.
Techniques sensitive to cell motion significantly enhance contrast for accurate perfusion and blood velocity assessments.
These methods offer revolutionary potential for understanding vascular regulation and managing retinal diseases.

Conclusions:

Noninvasive retinal imaging is transforming the study of ocular vascular health and disease.
Precise measurements of blood flow and oxygen delivery are becoming feasible.
This technology holds significant promise for improving the diagnosis and treatment of retinal vascular conditions.