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Published on: August 21, 2017
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Acute Flaccid Myelitis.
William Ide1, Michelle Melicosta2, Melissa K Trovato1
1Department of Pediatric Rehabilitation, Kennedy Krieger Institute, 707 North Broadway, Ste. 232, Baltimore, MD 21205, USA; Department of Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine.
Summary
Acute flaccid myelitis (AFM) is a neurologic disorder causing muscle weakness and paralysis, often linked to enteroviral infections. This review covers AFM
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Acute flaccid myelitis (AFM) is a rare neurologic condition characterized by sudden muscle weakness.
- AFM presents with epidemic patterns and is incompletely understood.
- Enteroviral infections are frequently associated with AFM outbreaks.
Purpose of the Study:
- To review the current understanding of acute flaccid myelitis (AFM).
- To consolidate information on AFM's definition, epidemiology, and associations.
- To describe clinical presentation, diagnostics, management, and rehabilitation.
Main Methods:
- Literature review of current research on acute flaccid myelitis.
- Analysis of case definitions, epidemiological data, and enteroviral associations.
- Synthesis of information on clinical features, diagnostic tools, and treatment strategies.
Main Results:
- AFM causes weakness ranging from mild paresis to severe paralysis.
- Diagnostic investigations, including electrodiagnostics, are crucial for AFM.
- Management includes acute care, surgical options, and rehabilitation.
Conclusions:
- Further research is needed to fully understand AFM.
- Comprehensive management strategies are essential for AFM patients.
- Early diagnosis and intervention improve outcomes for acute flaccid myelitis.
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