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Exercise and Nutraceuticals: Eminent Approach for Diabetic Neuropathy.

Mayur Bhimrao Kale¹, Komal Bajaj¹, Mohit Umare¹

¹Shrimati Kishoritai Bhoyar College of Pharmacy, New Kamptee, Nagpur 441002, Maharashtra,India.

Current Molecular Pharmacology

|June 30, 2021

Summary

Physical exercise and herbal therapies can significantly reduce the debilitating effects of diabetic neuropathy. These natural approaches offer promising benefits for nerve health and managing this common diabetes complication.

Keywords:

Diabetes Mellitus diabetic ketoacidosis diabetic neuropathy nonketotic hyperosmolar state nutraceuticals physical exercise

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Area of Science:

Neurology
Endocrinology
Integrative Medicine

Background:

Diabetic neuropathy affects approximately 50% of diabetes mellitus patients, causing severe nerve damage.
This condition impacts autonomic, sensory, and motor neurons, leading to significant disabilities and poor recovery.
The pathophysiology of diabetic neuropathy is diverse and complex.

Purpose of the Study:

To review the therapeutic benefits of physical exercise and herbal/nutraceutical therapies for diabetic neuropathy.
To explore the mechanisms of action for these non-pharmacological interventions.
To assess the safety and efficacy of exercise and nutraceuticals in managing diabetic neuropathy.

Main Methods:

Literature review of public domain studies on exercise, herbal extracts, and nutraceuticals.
Emphasis on therapeutic actions and beneficial effects in diabetic neuropathy.
Analysis of scientific evidence for prevention and treatment strategies.

Main Results:

Physical exercise, including aerobic activities and weight lifting, shows effectiveness in managing diabetic neuropathy.
Herbal extracts and nutraceuticals demonstrate antioxidant, anti-inflammatory, analgesic, and neuroprotective properties.
Combined exercise and nutraceutical therapy offers a promising approach with rare adverse events.

Conclusions:

Routine physical exercise and consistent use of herbal/nutraceuticals are effective in treating and preventing diabetic neuropathy.
These therapies offer novel mechanisms, including improved vascular and neuronal health.
Exercise and nutraceuticals represent safe and beneficial adjuncts to standard diabetic neuropathy care.