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SARS CoV-2: a review of current treatment regimens
1Eunice Kennedy Shriver National Institute of Child Health and Human Development.
Abstract:
SARS CoV-2, otherwise known as Corona virus 2019 (COVID-19) has left >300,000 dead without a definitive cure in sight. Significant research has been conducted regarding the use of currently available pharmacotherapies and multiple clinical trials are underway to bring new treatments to market. While supportive treatment remains the standard of care, additional therapeutic regimens including antivirals, monoclonal antibodies, antibiotics, anti-inflammatories, immunoenhancers, vitamins, systemic steroids, inhalants, anticoagulants, and convalescent plasma are showing promise.
Insights
The COVID-19 pandemic has caused over 300,000 deaths globally. Research is exploring various treatments beyond supportive care, including antivirals and immune-boosting therapies, to combat the virus.
Area of Science:
- Infectious Diseases
- Virology
- Pharmacology
Background:
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, has resulted in a significant global mortality rate exceeding 300,000 deaths.
- The absence of a definitive cure necessitates urgent exploration of diverse therapeutic strategies.
Purpose of the Study:
- To review current research on pharmacotherapies for COVID-19.
- To highlight promising therapeutic regimens beyond standard supportive care.
Main Methods:
- Review of existing scientific literature on COVID-19 treatments.
- Analysis of ongoing clinical trials for novel therapeutic agents.
Main Results:
- Supportive treatment remains the cornerstone of COVID-19 care.
- Multiple therapeutic avenues are under investigation, showing potential efficacy.
Conclusions:
- A range of treatments including antivirals, monoclonal antibodies, and immunomodulators are being actively researched.
- Convalescent plasma and various supportive medications also show promise in managing COVID-19.
- Continued research and clinical trials are crucial for developing effective COVID-19 treatments.
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