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Updated: Oct 31, 2025

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
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Alkylsulfenyl thiocarbonates: precursors to hydropersulfides potently attenuate oxidative stress

Vinayak S Khodade1, Sahil C Aggarwal1, Blaze M Pharoah1

  • 1Department of Chemistry, Johns Hopkins University Baltimore Maryland 21218 USA jtoscano@jhu.edu.

Chemical Science
|July 1, 2021
PubMed

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Thiols and sulfides are sulfur analogs of alcohols and ethers, respectively, where the sulfur atom takes the place of the oxygen atom. Thus, thiols are generally represented as RSH, where R is an alkyl substituent and —SH is the functional group. On the other hand, in sulfides, the central sulfur atom is bonded to two hydrocarbon groups on either side. Depending upon the type of group, sulfides can be either symmetrical or asymmetrical. Both thiols and sulfides display a bent geometry,...
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