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Updated: Oct 31, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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Diversity-orientated synthesis of macrocyclic heterocycles using a double SNAr approach

Piotr Raubo1, Rodrigo J Carbajo1, William McCoull1

  • 1Medicinal Chemistry, Research and Early Development, Oncology R&D, AstraZeneca, Cambridge, UK. piotr.raubo@astrazeneca.com.

Organic & Biomolecular Chemistry
|July 1, 2021
PubMed

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