Applied Proteomics in 'One Health'

Area of Science:

• * Proteomics and One Health
• * Interdisciplinary research connecting human, animal, and environmental health through protein analysis.

Background:

• * The One Health concept emphasizes the interdependence of human, animal, and ecosystem health.
• * Proteomics enables the identification and quantification of proteins, crucial for understanding biological processes and disease states.

Purpose of the Study:

• * To review the application of proteomics technologies within the One Health framework.
• * To evaluate the role of proteomics in elucidating diseases and situations relevant to One Health.

Main Methods:

• * Literature review of proteomics applications in zoonotic infections, antibiotic resistance, and food safety.
• * Analysis of proteomics' role in studying pathogenetic pathways, transmission dynamics, biomarkers, and novel treatments.

Main Results:

• * Proteomics aids in understanding zoonotic infections (prion, viral, bacterial, protozoan, metazoan).
• * Applications include studying antibiotic resistance mechanisms, discovering treatments, and ensuring food safety (allergen detection, adulteration, pathogen identification).

Conclusions:

• * Proteomics is a valuable tool for advancing the One Health agenda.
• * Future sensitive protein analysis will enhance biomarker discovery and clinical applications, further supporting One Health initiatives.