Related Experiment Video
Updated: Oct 30, 2025

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
Epidemiology, Pathophysiology, and Management Strategies of Neonatal Wound Care
Yomna Amer1, Catherine Bridges2,3, Kalyani Marathe3
1School of Medicine, University of Louisville, Louisville, KY.
Insights
This review addresses the lack of guidelines for neonatal skin care, offering strategies for preventing and managing neonatal skin breakdown. It covers wound healing, skin fragility, and specific wound types to improve infant skin health.
Area of Science:
- Neonatal dermatology
- Wound healing and management
Background:
- Neonatal skin care guidelines are limited, leading to inconsistent management of skin breakdown.
- Neonatal skin is uniquely fragile, increasing susceptibility to injury and breakdown.
Purpose of the Study:
- To review the pathology and healing phases of wounds.
- To identify reasons for neonatal skin fragility.
- To provide evidence-based strategies for neonatal wound prevention and management.
Main Methods:
- Comprehensive literature review on neonatal skin conditions and wound care.
- Analysis of wound healing phases, skin pathology, and common neonatal wounds.
- Evaluation of prevention, care, dressing, and management strategies.
Main Results:
- Discusses moisture retention for wound healing, pressure ulcer classification, and the use of negative pressure wound therapy and silver dressings.
- Details prevention and treatment for surgical, extravasation, congenital, and thermal wounds.
- Provides methods to differentiate these wounds from diaper and contact dermatitis.
Conclusions:
- Establishing clear guidelines for neonatal wound care is crucial.
- A comprehensive approach to prevention and management is necessary to protect fragile neonatal skin.
Abstract:
Guidelines for neonatal skin care are scarce, and there is no consensus on the best management practices for neonatal skin breakdown. This review presents the pathology and phases of wound healing, reasons for neonatal skin fragility, and approaches to recognition of commonly encountered neonatal wounds. This review also provides general strategies for neonatal wound prevention, care, dressing, and management to avoid further damage to the fragile neonatal skin. The importance and role of retaining moisture in expediting wound healing is discussed, as well as updated classifications on how to grade and assess pressure ulcers and the role of negative pressure wound therapy and silver dressings. Lastly, this review discusses prevention and treatment options for surgical wounds, intravenous extravasation wounds, congenital wounds, and thermal injuries, in addition to how to differentiate these wounds from the common diaper dermatitis and contact dermatitis.
Related Concept Videos
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Phases of Wound Repair
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Hand hygiene
Hand washing...
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Peripheral Artery Disease IV: Nursing Management

