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Canine and feline haemangiosarcoma.

Maureen A Griffin1, William T N Culp1, Robert B Rebhun1

  • 1School of Veterinary Medicine, University of California-Davis, Davis, California, USA.

The Veterinary Record
|July 2, 2021
PubMed
Summary

Haemangiosarcoma (HSA) in dogs and cats is a common cancer with a poor prognosis, though some forms are less aggressive. Treatment involves surgery and chemotherapy, with new options being explored.

Area of Science:

  • Veterinary Oncology
  • Comparative Pathology

Background:

  • Haemangiosarcoma (HSA) is a malignant neoplasm in dogs and cats, likely originating from bone marrow progenitors.
  • Its pathogenesis is complex and multifactorial.

Purpose of the Study:

  • To review the clinical presentation and progression of various Haemangiosarcoma forms in dogs and cats.
  • To systematically review published treatment options and outcomes for veterinary Haemangiosarcoma.

Main Methods:

  • Literature search and review of pertinent scientific articles.
  • Summarization of identified literature for manuscript inclusion.

Main Results:

  • Dogs are diagnosed with HSA more frequently than cats.
  • Common primary sites include skin, muscle, and spleen; metastasis is typically rapid, leading to a poor prognosis.

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  • Cutaneous HSA may have a less aggressive course and better outcomes.

    • Conclusions:

    • Surgical excision and anthracycline-based chemotherapy are standard treatments for canine and feline HSA.
    • Novel treatment modalities are under investigation for Haemangiosarcoma.