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Related Experiment Videos

The allergens in cosmetics.

A C de Groot1, D P Bruynzeel, J D Bos

  • 1Department of Dermatology, Carolus and Willem-Alexander Hospital, 's-Hertogenbosch, The Netherlands.

Archives of Dermatology
|October 1, 1988
PubMed
Summary

The most common cause of cosmetic allergies is preservatives, particularly Kathon CG (methylisothiazolinone/methyl chloroisothiazolinone). Skin care products are the leading culprit in cosmetic-related contact dermatitis.

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Letter to the editor.

International journal of cosmetic science·2009

Area of Science:

  • Dermatology
  • Allergology
  • Cosmetic Science

Background:

  • Cosmetic products are widely used globally.
  • Contact dermatitis is a common adverse reaction to cosmetic ingredients.
  • Identifying specific allergens is crucial for patient management and product safety.

Purpose of the Study:

  • To identify the specific ingredients causing allergic contact dermatitis in patients using cosmetic products.
  • To determine the types of cosmetic products most frequently associated with allergic reactions.
  • To rank the prevalence of different cosmetic allergens.

Main Methods:

  • Retrospective analysis of 119 patients diagnosed with cosmetic-related contact dermatitis.
  • Patch testing to identify specific allergens.

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  • Categorization of reactions by cosmetic product type and ingredient class.

    • Main Results:

    • Skin care products were the most frequent cause (56.3%), followed by nail (13.4%), perfume (8.4%), and hair cosmetics (5.9%).
    • Preservatives were the most common allergen class (32.0%), followed by fragrances (26.5%) and emulsifiers (14.3%).
    • Kathon CG (methylisothiazolinone/methyl chloroisothiazolinone) was the most significant allergen (27.7%), followed by toluenesulfonamide/formaldehyde resin (12.6%) and oleamidopropyl dimethylamine (10.9%).

    Conclusions:

    • Preservatives, especially Kathon CG, are major causes of cosmetic-related allergic contact dermatitis.
    • Skin care products and nail cosmetics are frequently implicated in these reactions.
    • Understanding common allergens aids in diagnosing and preventing cosmetic allergies.