Related Experiment Video
Updated: Oct 30, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
Imaging striae distensae: a comparison between PS-OCT and digital dermoscopy
Wai Ching Lin1, Robert A Byers1,2, Wei Li1
1Department of Electronic and Electrical Engineering, University of Sheffield, Sir Frederick Mappin Building, Sheffield, S1 3JD, UK.
Quantifying stretch mark severity using polarization-sensitive optical coherence tomography (PS-OCT) may offer a more objective measure than visual scoring. PS-OCT revealed significantly higher skin birefringence in stretch marks compared to normal skin.
Area of Science:
- Dermatology
- Biomedical Optics
- Medical Imaging
Background:
- Stretch marks (striae distensae) are common skin conditions that can cause significant emotional distress.
- Objective and reliable methods for quantifying stretch mark severity are needed to assess treatment efficacy and patient well-being.
Purpose of the Study:
- To compare the effectiveness of visual scoring using clinical imaging versus polarization-sensitive optical coherence tomography (PS-OCT) for quantifying stretch mark severity.
- To investigate the relationship between visual assessment and optical properties of stretch marks.
Main Methods:
- Collected data from 19 volunteers, including visually normal skin and skin affected by stretch marks.
- Images of stretch marks were captured using a clinical visible-light dermatological camera (C-Cube).
- Local skin birefringence was measured using polarization-sensitive optical coherence tomography (PS-OCT).
Main Results:
- A weak correlation was observed between visual scores from C-Cube images and PS-OCT birefringence values.
- Skin affected by stretch marks exhibited significantly higher birefringence values compared to visually normal skin.
- PS-OCT provides a distinct optical signature for stretch marks.
Conclusions:
- PS-OCT shows potential as an objective tool for quantifying stretch mark severity.
- Birefringence measurement using PS-OCT may offer a more sensitive method than visual scoring for detecting changes in stretch mark tissue.
- Further research is warranted to validate PS-OCT for clinical assessment of striae distensae.
More Related Videos
07:05Correlative Optical Spectroscopy and Mass Spectrometry Imaging Methodology to Visualise Drug Distribution in a Soft Tissue Section
Published on: June 20, 2025
09:37Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022