Laparoscopic Partial Gastrectomy for Large Gastric GISTs.

Area of Science:

• Surgical Oncology
• Gastroenterology
• Minimally Invasive Surgery

Background:

• Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the GI tract.
• The stomach is the most frequently affected site, accounting for 50-60% of GISTs.
• The safety and feasibility of laparoscopic surgery for gastric GISTs larger than 5 cm remain under investigation.

Purpose of the Study:

• To evaluate the safety and feasibility of laparoscopic partial gastrectomy for large gastric GISTs.
• To assess the outcomes of laparoscopic resection for gastric GISTs of various sizes.

Main Methods:

• A retrospective study of 30 patients with gastric GISTs who underwent laparoscopic partial gastrectomy between December 2013 and January 2021.
• Data collected included tumor location, size, operative time, estimated blood loss, hospital stay, and follow-up period.

Main Results:

• The mean tumor size was 9.5 cm (range 5-17 cm), with the most common location being the greater curvature (46.7%).
• Mean operative time was 152.67 minutes, with a mean estimated blood loss of 139.33 ml.
• Mean hospital stay was 3.53 days, with a mean follow-up of 32.4 months.

Conclusions:

• Laparoscopic resection is a feasible approach for gastric GISTs, including large tumors.
• Patients with large gastric GISTs achieve outcomes comparable to those with smaller tumors.
• Neoadjuvant therapy may be considered for large GISTs to facilitate laparoscopic resection.