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Published on: August 8, 2025
Parathyroid hemangioma
Odille Mejia1, Hisham F Bahmad1, Kei Shing Oh1
1Mount Sinai Medical Center, Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Miami Beach, FL, USA.
Parathyroid hemangiomas are rare vascular tumors that can mimic common parathyroid conditions. This case highlights the importance of considering hemangiomas in the differential diagnosis of parathyroid gland enlargement and primary hyperparathyroidism.
Area of Science:
- Endocrinology
- Surgical Pathology
- Vascular Neoplasms
Background:
- Hemangiomas are benign capillary neoplasms resulting from developmental anomalies.
- While common in the head and neck, parathyroid hemangiomas are exceptionally rare.
- Only five prior cases of parathyroid hemangiomas have been documented in medical literature.
Purpose of the Study:
- To report an additional case of parathyroid hemangioma.
- To emphasize the clinical and radiographic mimicry of this rare entity.
- To raise awareness among surgeons regarding this differential diagnosis.
Main Methods:
- Case presentation of a 68-year-old male patient.
- Detailed gross pathological description of the parathyroid hemangioma.
- Association with primary hyperparathyroidism was noted.
Main Results:
- A hemangioma was found to almost entirely replace the right upper parathyroid gland.
- The tumor measured 1.3 × 1.3 × 1.2 cm and weighed 700 mg.
- The patient presented with primary hyperparathyroidism.
Conclusions:
- Parathyroid gland enlargement caused by vascular neoplasms can resemble hyperplasia or adenomas.
- Surgeons must consider parathyroid hemangiomas in the differential diagnosis of hyperparathyroidism.
- Awareness of this rare entity is crucial for accurate diagnosis and management.
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