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Updated: Oct 29, 2025
Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Thyroid Embolization for Nonsurgical Treatment of Nodular Goiter: A Single-Center Experience in 56 Consecutive
Saim Yilmaz1, Hatice Arıöz Habibi1, Akin Yildiz2
1Varisson Radiology Center, Yeşilbahçe Mah, Metin Kasapoğlu Cad Nuri Mancar Apt, D:No:42/A, 07160 Muratpaşa/Antalya, Turkey.
Purpose:
To investigate the safety and efficacy of thyroid artery embolization (TAE) in the treatment of nodular goiter (NG).
Methods:
During a 5.5-year period, 56 consecutive patients with a NG underwent TAE. In Group A, there were 20 patients with a solitary/dominant 5-11-cm nodule, and in Group B, there were 36 patients with numerous nodules. Of the 56 patients, 47 (84%) had a retrosternal goiter and 25 had hyperthyroidism. In all patients, clinical and radiological evaluations were made at baseline and 6 months after TAE, and these parameters were statistically compared.
Results:
In 56 patients, 145 of the 146 thyroid arteries were successfully embolized. The 30-day mortality rate was 1.8%. Minor and major complications occurred in 25 and 2 patients, respectively. Six months after the TAE, the mean nodule volume was reduced from 80.2 mL to 25.0 mL, the mean thyroid volume was reduced from 147.0 mL to 62.6 mL, and the mean intrathoracic extension was reduced from 31.7 mm to 15.9 mm (P < .001). Of the 22 patients with non-Graves hyperthyroidism, 19 (86%) became euthyroid. The mean thyroid-related patient-reported outcome scores improved from 155.4 to 70.4 (P < .001). Of the 51 patients, 50 (98%) declared that they would recommend TAE to other patients with NG.
Conclusions:
TAE is safe and effective for the treatment of NG, with a significant volume reduction of the nodule(s) and thyroid gland.
