Related Experiment Video
Updated: Oct 28, 2025

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Mucosal defect closure after duodenal endoscopic submucosal dissection using the reopenable-clip over the line method
Tatsuma Nomura1,2, Shinya Sugimoto2, Nobuyuki Tsuda2
1Department of Gastroenterology Mie Prefectural Shima Hospital Shima Japan.
Closure of large duodenal mucosal defects after endoscopic submucosal dissection (ESD) is now reliably achieved using the reopenable-clip over the line method (ROLM). This technique ensures complete closure, preventing adverse events and improving patient outcomes.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Surgical Innovation
Background:
- Effective closure of mucosal defects following duodenal endoscopic submucosal dissection (ESD) is critical for preventing postoperative complications.
- Previous methods included underwater clip closure and clip-line techniques.
- The reopenable-clip over the line method (ROLM) was developed for complete closure of mucosal defects, including margins and muscular layers.
More Related Videos
20:33A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
Published on: July 4, 2019
05:57ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
Published on: February 10, 2017