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CAN COMPLETE BLOOD CELL COUNT PARAMETERS PREDICT DEEP VEIN THROMBOSIS?
Kevser Tural1, Fatih Kara1, Sema Avcı1
11Kafkas University, Medical Faculty, Department of Cardiovascular Surgery, Kars, Turkey; 2Kafkas University, Medical Faculty, Department of Biochemistry, Kars, Turkey; 3Amasya University, Medical Faculty, Department of Emergency Medicine, Amasya, Turkey; 4Kafkas University, Medical Faculty, Department of Internal Medicine, Kars, Turkey.
Acta Clinica Croatica
|July 21, 2021
Summary
Complete blood count parameters like neutrophil to lymphocyte ratio and hemoglobin can help predict deep vein thrombosis (DVT). These markers, along with hypertension and anemia, are independent risk factors for DVT.
Area of Science:
- Hematology
- Vascular Medicine
- Diagnostic Markers
Background:
- Deep vein thrombosis (DVT) is a significant vascular condition.
- Predictive markers for DVT are crucial for early diagnosis and management.
- Complete blood cell (CBC) count parameters warrant investigation as potential DVT indicators.
Purpose of the Study:
- To evaluate the predictive value of CBC parameters for deep vein thrombosis (DVT).
- To identify specific red blood cell, white blood cell, and platelet indices associated with DVT.
- To determine independent risk factors for DVT among CBC parameters and clinical conditions.
Main Methods:
- Retrospective case-control study involving 71 DVT patients and 142 controls.
- Analysis of complete blood cell count parameters, including red blood cell indices, white blood cell subtypes, and platelet indices.
- Comparison of CBC parameters and clinical characteristics between DVT and non-DVT groups, with statistical analysis.
Main Results:
- Patients with DVT showed higher frequencies of hypertension, diabetes mellitus, COPD, chronic renal failure, and coronary arterial disease.
- Lower hemoglobin and lymphocyte counts, and higher red blood cell distribution width, neutrophil, neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR) were observed in the DVT group.
- Hypertension, anemia, NLR, and PLR were identified as independent risk factors for DVT.
Conclusions:
- Neutrophil to lymphocyte ratio (NLR) and hemoglobin levels may serve as novel, cost-effective diagnostic tools for DVT.
- Hypertension, anemia, NLR, and PLR are significant independent risk factors for deep vein thrombosis.
- CBC parameters offer valuable insights into DVT prediction and risk stratification.
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