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Agreement between Compass Fundus Perimeter New Grid and 10-2 Testing Protocols for Detecting Central Visual
Nevin W El-Nimri1, Rafaella C Penteado1, Christopher Bowd1
1Hamilton Glaucoma Center, Shiley Eye Institute, and the Viterbi Family Department of Ophthalmology, University of California San Diego, La Jolla, California.
Ophthalmology. Glaucoma
|July 22, 2021
Summary
The Compass New Grid (NG) test shows fair to moderate agreement with the 10-2 protocol for detecting early glaucomatous defects. NG offers higher specificity, making it valuable for specific clinical uses in glaucoma detection.
Area of Science:
- Ophthalmology and Visual Science
- Medical Technology and Diagnostics
Background:
- Early detection of glaucomatous defects in the central visual field is crucial for timely intervention.
- Standard automated perimetry protocols like the 10-2 test are widely used, but newer methods are emerging.
Purpose of the Study:
- To evaluate the diagnostic agreement between the Compass New Grid (NG) and the 10-2 test protocols.
- To assess the ability of both protocols in detecting early glaucomatous defects within the central 10 degrees of the visual field (CVFD).
Main Methods:
- A cross-sectional study involving 123 eyes from healthy individuals, glaucoma suspects, and glaucoma patients.
- Subjects underwent both NG and 10-2 Compass automated perimetry testing.
- Agreement was assessed using Cohen's Kappa statistic; sensitivity and specificity were calculated using OCT macula deviation maps.
Main Results:
- Fair to moderate agreement was found between NG and 10-2 for detecting superior and inferior CVFDs on both Total Deviation (TD) and Pattern Deviation (PD) plots.
- The NG protocol demonstrated consistently higher specificity compared to the 10-2 test for both TD and PD plots.
- Sensitivity of the NG protocol was consistently lower than the 10-2 test.
Conclusions:
- While the Compass NG detected fewer central visual field defects (CVFDs) than the 10-2 protocol, it identified unique defects in early glaucoma patients.
- The NG protocol may be particularly beneficial in clinical settings prioritizing higher specificity or utilizing the Pattern Standard Deviation (PSD) criterion for glaucoma assessment.
