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Measuring adherence to therapy in airways disease
Joshua Holmes1, Liam G Heaney1
1Wellcome Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.
Breathe (Sheffield, England)
|July 23, 2021
Summary
Accurately measuring medication adherence in airways disease is crucial for effective treatment and reducing healthcare use. This review explores various adherence measurement methods and their clinical application with biomarkers.
Area of Science:
- Pulmonary Medicine
- Pharmacology
- Clinical Pharmacy
Background:
- Medication non-adherence significantly impacts airways disease control and healthcare utilization.
- Accurate adherence assessment is vital for optimizing therapy and preventing unnecessary treatment escalation.
- Interpreting adherence measures with biomarkers can reveal impacts on disease control.
Purpose of the Study:
- To review common methods for measuring medication adherence in patients with airways disease.
- To discuss the application of adherence measures alongside clinical biomarkers in routine care.
Main Methods:
- Review of common adherence measurement techniques: patient self-report, prescription record checks, canister weighing, dose counting, drug level monitoring, and electronic monitoring.
- Discussion of the advantages and limitations of each method.
- Exploration of integrating adherence measures with disease control biomarkers.
Main Results:
- Multiple methods exist for measuring medication adherence, each with unique benefits and drawbacks.
- Effective use requires understanding the nuances of each technique.
- Combining adherence data with biomarker analysis offers deeper insights into treatment efficacy.
Conclusions:
- Various adherence measurement tools are available for airways disease, each with specific applications and limitations.
- Integrating adherence monitoring with biomarker assessment is key to improving disease management.
- Clinicians should select appropriate adherence measures and interpret them in the context of patient biomarkers.
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