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Three-dimensional measurement and analysis of benign prostatic hyperplasia
Yankun Feng1, Jianhui Wu2, He Zhu3
1Department of Anatomy and Histology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Translational Andrology and Urology
|July 23, 2021
Summary
Benign prostatic hyperplasia (BPH) anatomical features like intravesical prostatic protrusion increase with age and larger prostate volume. Three-dimensional (3D) imaging reveals significant changes in BPH, aiding research.
Area of Science:
- Urology
- Medical Imaging
- Anatomy
Background:
- Benign prostatic hyperplasia (BPH) anatomical characteristics, particularly intravesical prostatic protrusion (IPP), remain understudied.
- Investigating the influence of age and prostate volume on BPH anatomy is crucial for understanding disease progression.
Purpose of the Study:
- To determine the effects of patient age and prostate volume on the anatomical features of benign prostatic hyperplasia (BPH).
- To utilize three-dimensional (3D) measurement techniques for detailed analysis of BPH-related anatomical changes.
Main Methods:
- Retrospective analysis of 98 patients diagnosed with benign prostatic hyperplasia (BPH).
- Reconstruction of 3D models from pelvic T2-weighted MRI scans, including prostate, central gland, peripheral zone, IPP, and prostatic urethra.
- Measurement of various volumetric and dimensional parameters, including IPP volume, thickness, index, prostate volume, and peripheral zone characteristics.
Main Results:
- Higher intravesical prostatic protrusion (IPP) volume, IPP thickness, and peripheral zone volume were observed in patients with prostate volume >80 mL compared to those with <80 mL (P<0.001, 0.01, 0.01).
- These parameters, along with IPP volume and thickness, significantly increased with age (P<0.001, 0.01, 0.05).
- Peripheral zone index decreased with age (P<0.01) and was lower in larger prostates (P<0.05), while IPP index, peripheral zone thickness, and prostatic urethra thickness showed no significant group differences.
Conclusions:
- The study highlights that intravesical prostatic protrusion (IPP) volume and thickness are significantly influenced by prostate size and patient age.
- Three-dimensional (3D) imaging and measurement provide valuable insights into the anatomical alterations associated with benign prostatic hyperplasia (BPH).
- The findings support the utility of 3D measurements for advancing clinical and scientific research in BPH.
