Fascinating MXene nanomaterials: emerging opportunities in the biomedical field

In recent years, there has been rapid progress in MXene research due to its distinctive two-dimensional structure and outstanding properties. Especially in biomedical applications, MXenes have attracted widespread favor with numerous studies on biosafety, bioimaging, therapy, and biosensing, although their development is still in the experimental stage. A comprehensive understanding of the current status of MXenes in biomedicine will promote their use in clinical applications. Here, we review advances in MXene research. First, we introduce the methods of synthesis, surface modification and functionalization of MXenes. Then, we summarize the biosafety and biocompatibility, paving the way for specific biomedical applications. On this basis, MXene nanostructures are described with respect to their use in antibacterial, bioimaging, cancer therapy, tissue regeneration and biosensor applications. Finally, we discuss MXene as a promising candidate material for further applications in biomedicine.