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Related Concept Videos

Stress and Mental Health01:30

Stress and Mental Health

276
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
276
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

98
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
98
Depression: Overview01:18

Depression: Overview

489
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
489
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

130
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
130
Diagnostic and Statistical Manual of Mental Disorders (DSM)01:27

Diagnostic and Statistical Manual of Mental Disorders (DSM)

333
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
333
Factors Affecting Illness01:18

Factors Affecting Illness

4.7K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
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Related Experiment Video

Updated: Oct 26, 2025

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
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Why is COVID-19 associated with mental illness?

Maxime Taquet1,2, Paul J Harrison1,2

  • 1Department of Psychiatry, University of Oxford, Oxford, UK.

Med (New York, N.Y.)
|July 26, 2021
PubMed
Summary

The COVID-19 pandemic negatively impacts mental health. A COVID-19 diagnosis increases subsequent mental illness risk, while psychiatric conditions heighten COVID-19 infection risk, a connection explored in this study.

Area of Science:

  • Psychiatry
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic has significantly affected global mental health.
  • Emerging evidence indicates a bidirectional relationship between COVID-19 and mental illness.

Purpose of the Study:

  • To explore the underlying reasons for the increased risk of mental illness following a COVID-19 diagnosis.
  • To investigate the factors contributing to the heightened susceptibility to COVID-19 infection in individuals with pre-existing psychiatric conditions.

Main Methods:

  • Literature review of existing studies on COVID-19 and mental health.
  • Analysis of epidemiological data and clinical observations.
  • Discussion of potential biological and psychosocial mechanisms.

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Related Experiment Videos

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Main Results:

  • COVID-19 infection is associated with an elevated risk of developing new-onset mental health disorders.
  • Individuals with mental health conditions exhibit a greater vulnerability to severe COVID-19 outcomes.
  • Bidirectional pathways involving immune response, neurological effects, and social determinants are implicated.

Conclusions:

  • The pandemic poses a dual threat to mental well-being, impacting both incidence and severity.
  • Understanding these complex interactions is crucial for integrated healthcare strategies.
  • Further research is warranted to elucidate specific mechanisms and inform targeted interventions.