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The association of PRECISE-DAPT score with thrombus burden in patients with ST-segment elevation myocardial

Faysal Şaylık1, Tayyar Akbulut1

  • 1Department of Cardiology, Van Training and Research Hospital, Health Science University, Van, Turkey.

Acta Cardiologica
|July 26, 2021
PubMed

Insights

The PRECISE-DAPT score predicts high thrombus burden in ST-segment elevation myocardial infarction (STEMI) patients. This score is an independent predictor of increased thrombus burden, aiding risk assessment in STEMI care.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Biomarkers

Background:

  • Intracoronary thrombus in ST-segment elevation myocardial infarction (STEMI) correlates with adverse outcomes.
  • The PRECISE-DAPT score assesses bleeding risk in STEMI patients on dual antiplatelet therapy.
  • Previous studies link the PRECISE-DAPT score to cardiovascular events.

Purpose of the Study:

  • To investigate the association between the PRECISE-DAPT score and thrombus burden in STEMI patients.
  • To determine if the PRECISE-DAPT score can predict high thrombus burden (HTB) in STEMI.

Main Methods:

  • Retrospective analysis of 204 STEMI patients undergoing primary percutaneous coronary intervention.
  • Calculation of thrombus burden grade and PRECISE-DAPT score for all subjects.
  • Comparison of PRECISE-DAPT scores between high (grades 4-5) and low (grades 1-3) thrombus burden groups.

Main Results:

  • Patients with high thrombus burden (HTB) had significantly higher PRECISE-DAPT scores than those with low thrombus burden (LTB) (p < .0001).
  • The mean age in the HTB group was 63.7 years, with 64.7% males.
  • PRECISE-DAPT score, troponin I, ejection fraction, and pain-to-balloon time independently predicted HTB.

Conclusions:

  • The PRECISE-DAPT score is an independent predictor of high thrombus burden in STEMI patients.
  • This finding suggests the PRECISE-DAPT score may offer insights into thrombotic risk beyond bleeding risk in STEMI.
Abstract

Keywords:
PRECISE-DAPT scoreST-segment elevation myocardial infarctionThrombus burden

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