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Bilateral Multifocal Choroiditis following COVID-19 Vaccination
Mallika Goyal1, Somasheila I Murthy2, Sridhar Annum1
1Department of Retina-vitreous and Uveitis, Ophthalmology, Apollo Hospitals, Hyderabad, India.
Ocular Immunology and Inflammation
|August 4, 2021
Summary
COVID-19 vaccination can trigger bilateral choroiditis, an inflammatory eye condition. Prompt corticosteroid treatment led to rapid visual recovery in a case report.
Area of Science:
- Ophthalmology
- Immunology
- Vaccinology
Background:
- The COVID-19 pandemic necessitated rapid vaccine development.
- Adverse events following immunization (AEFIs) are monitored for vaccine safety.
- Ocular inflammatory conditions can be triggered by various stimuli.
Observation:
- A 34-year-old male experienced sudden visual loss one week post-second dose of COVID-19 vaccine.
- Ophthalmic examination revealed bilateral choroidal thickening and macula serous detachment in the right eye.
- Ocular ultrasonography confirmed severe choroidal thickening in both eyes.
Findings:
- The patient's visual acuity and ocular structures improved rapidly following oral corticosteroid therapy.
- Significant resolution of macular edema and choroidal thickening was observed within two weeks.
- Complete visual recovery was achieved subsequently.
Implications:
- This case suggests a potential link between COVID-19 vaccination and inflammatory/autoimmune ocular responses.
- Ophthalmologists should consider vaccination as a potential trigger for uveitis and related conditions.
- Early diagnosis and corticosteroid treatment are crucial for favorable visual outcomes in post-vaccination ocular inflammation.
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