Related Experiment Video
Updated: Oct 25, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
Published on: December 7, 2021
A generalizable data assembly algorithm for infectious disease outbreaks
Maimuna S Majumder1,2, Sherri Rose3
1Computational Health Informatics Program, Boston Children's Hospital, Boston, Massachusetts, USA.
Abstract:
During infectious disease outbreaks, health agencies often share text-based information about cases and deaths. This information is rarely machine-readable, thus creating challenges for outbreak researchers. Here, we introduce a generalizable data assembly algorithm that automatically curates text-based, outbreak-related information and demonstrate its performance across 3 outbreaks. After developing an algorithm with regular expressions, we automatically curated data from health agencies via 3 information sources: formal reports, email newsletters, and Twitter. A validation data set was also curated manually for each outbreak, and an implementation process was presented for application to future outbreaks. When compared against the validation data sets, the overall cumulative missingness and misidentification of the algorithmically curated data were ≤2% and ≤1%, respectively, for all 3 outbreaks. Within the context of outbreak research, our work successfully addresses the need for generalizable tools that can transform text-based information into machine-readable data across varied information sources and infectious diseases.
More Related Videos
Related Concept Videos
Steps in Outbreak Investigation
Statistical Methods for Analyzing Epidemiological Data
Principles of Disease Surveillance
Statistical Software for Data Analysis and Clinical Trials
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Genome Annotation and Assembly

