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Updated: Oct 25, 2025

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
Triterpenoids from the bark of Entandrophragma angolense
Binh T D Trinh1,2,3, Dzung N Bui1,3, Ly T T Nguyen1,3
1Natural Product and Medicinal Chemistry Lab, Faculty of Chemistry, VNUHCM-University of Science (HCMUS), Ho Chi Minh City, Vietnam.
Abstract:
Two new triterpenoids, entanolide (1) and methyl 3,4-secotirucalla-23-oxo-4(28),7,24-trien-21-al-3-oate (2), together with nine known compounds (3-11), were isolated from the bark of Entandrophragma angolense. Their structures were elucidated based on spectroscopic analyses, mainly 1 D and 2 D NMR spectral data. Compounds 1-6 and 8 were evaluated for their cytotoxicity against HepG2 cells, and compounds 2-5 exhibited weak activities.
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