Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Review and Preview01:13

Review and Preview

10.1K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
10.1K
Review and Preview01:10

Review and Preview

8.1K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.1K
Proofreading01:43

Proofreading

57.3K
Overview
57.3K
Proofreading01:31

Proofreading

7.2K
Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase...
7.2K
Journal Bearings01:23

Journal Bearings

861
Journal bearings are mechanical components that support and provide lateral stability to rotating shafts and axles. They are crucial in reducing friction, wear, and vibration in machinery such as engines, turbines, and pumps. The principle behind journal bearings is forming a thin lubricant film between the bearing surface and the rotating shaft, which minimizes direct contact and reduces frictional forces.
To better understand the concept of journal bearings, consider a rope winch with dry or...
861
Types of Selection01:46

Types of Selection

42.8K
Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...
42.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preoperative Imaging for Cochlear Implantation: A Global Consensus.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same author

Long-term in vivo pharmacokinetics of dexamethasone-loaded cochlear implant electrode carrier dummies with optimized release profiles.

Scientific reports·2026
Same author

The Bonebridge BCI 602 Safety and Performance 1 Year Post-Implantation in Adults and Children: A Multicentric Post-Market Study.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·2025
Same author

Hybrid neurofibroma/schwannoma in schwannomatosis-a diagnostically challenging benign peripheral nerve sheath tumour.

Familial cancer·2025
Same author

Acoustic simulation of cochlear implant sound to approximate the perceptual experience of electric hearing.

Scientific reports·2025
Same author

[Bone conduction and active middle ear implants: systematics and audiological indication criteria].

HNO·2025

Related Experiment Video

Updated: Oct 25, 2025

BioMEMS and Cellular Biology: Perspectives and Applications
16:30

BioMEMS and Cellular Biology: Perspectives and Applications

Published on: October 1, 2007

9.9K

Editorial.

Stefan K Plontke

    Laryngo- Rhino- Otologie
    |August 5, 2021
    PubMed
    Summary
    This summary is machine-generated.

    Rare diseases pose significant challenges for patients and healthcare providers, complicating research and care. "Lorenzo's Oil" highlights the diagnostic and therapeutic hurdles of rare conditions like adrenoleukodystrophy (ALD).

    More Related Videos

    Perspectives on Neuroscience
    26:41

    Perspectives on Neuroscience

    Published on: July 31, 2007

    5.1K
    Major Components of the Light Microscope
    08:08

    Major Components of the Light Microscope

    Published on: July 30, 2008

    23.8K

    Related Experiment Videos

    Last Updated: Oct 25, 2025

    BioMEMS and Cellular Biology: Perspectives and Applications
    16:30

    BioMEMS and Cellular Biology: Perspectives and Applications

    Published on: October 1, 2007

    9.9K
    Perspectives on Neuroscience
    26:41

    Perspectives on Neuroscience

    Published on: July 31, 2007

    5.1K
    Major Components of the Light Microscope
    08:08

    Major Components of the Light Microscope

    Published on: July 30, 2008

    23.8K

    Area of Science:

    • Neurology
    • Genetics
    • Rare Diseases

    Background:

    • Rare diseases, including adrenoleukodystrophy (ALD), present unique challenges in diagnostics, research, and treatment.
    • The rarity of these conditions complicates medical care and necessitates specialized approaches for affected patients and their families.

    Discussion:

    • The film "Lorenzo's Oil" serves as a poignant illustration of the multifaceted difficulties encountered in managing rare diseases.
    • Despite advancements, many challenges in rare disease research and therapy persist, impacting patients, families, and healthcare professionals.

    Key Insights:

    • "Lorenzo's Oil" brought public attention to the complexities of orphan diseases, using the true story of adrenoleukodystrophy (ALD).
    • The narrative underscores the critical need for increased focus and resources for rare disease research and patient support.

    Outlook:

    • Continued public and scientific focus on orphan diseases is crucial for advancing diagnostics and therapeutic strategies.
    • Addressing the medical and economic complexities of rare diseases requires collaborative efforts from researchers, clinicians, and policymakers.