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Biomarkers in Cardiorenal Syndrome

Giovanni Goffredo1,2, Roberta Barone1,2, Vito Di Terlizzi1,2

  • 1Department of Medical and Surgical Sciences, University of Foggia, Viale Luigi Pinto 1, 71122 Foggia, Italy.

Journal of Clinical Medicine
|August 7, 2021
PubMed

Insights

Cardiorenal syndrome involves complex heart and kidney interactions. This review explores new biomarkers to assess kidney function and predict worsening in cardiovascular patients.

Area of Science:

  • Cardiology
  • Nephrology
  • Biomarker Research

Background:

  • Cardiorenal syndrome (CRS) highlights the intricate relationship between heart and kidney diseases.
  • Accurate assessment of renal function is crucial in patients with cardiovascular conditions.
  • Identifying individuals at risk for acute or chronic kidney function decline is a clinical priority.

Purpose of the Study:

  • To review the clinical utility of novel biomarkers in managing cardiorenal syndrome.
  • To provide an overview of recent advancements in CRS biomarker research.
  • To identify biomarkers that can improve risk stratification in CRS patients.

Main Methods:

  • Literature review of recent studies on cardiorenal syndrome biomarkers.
  • Analysis of biomarker performance in assessing renal function.
  • Evaluation of biomarkers for predicting renal outcomes in cardiovascular disease.

Main Results:

  • Emerging biomarkers show promise in evaluating renal status in CRS.
  • Certain biomarkers may help identify patients at higher risk of renal deterioration.
  • The clinical application of these biomarkers requires further validation.

Conclusions:

  • New biomarkers offer potential for improved management of cardiorenal syndrome.
  • Further research is needed to establish the definitive role of these biomarkers in clinical practice.
  • Biomarker-guided strategies could enhance patient care in CRS.

Keywords:
acute kidney injurybiomarkerscardio-renal syndromeheart failurerenal function

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