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Toward a better understanding of persistent headache after mild COVID-19: Three migraine-like yet distinct scenarios

Edoardo Caronna1,2, Alicia Alpuente1,2, Marta Torres-Ferrus1,2

  • 1Headache Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.

Headache
|August 7, 2021
PubMed

Insights

Persistent headaches after COVID-19 infection are common, but this "post-COVID headache" term covers diverse presentations. Careful evaluation is crucial for understanding these complex, migraine-like symptoms and their causes.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Public Health

Background:

  • Coronavirus disease 2019 (COVID-19) has led to a rise in persistent post-infection symptoms.
  • Headache is a frequently reported sequela, with
  • post-COVID headache
  • becoming a common referral reason.

Observation:

  • This report details three cases of individuals experiencing migraine-like headaches following mild COVID-19 infections.
  • These cases illustrate the varied clinical presentations within the umbrella term
  • post-COVID headache
  • .

Findings:

  • The term
  • post-COVID headache
  • encompasses a range of headache types, not a single entity.
  • Migraine-like headaches represent one significant phenotype of persistent post-COVID neurological symptoms.

Implications:

  • Accurate diagnosis and phenotyping of post-COVID headaches are essential for effective patient management.
  • Further research into the distinct pathophysiological mechanisms underlying different post-COVID headache types is warranted.

Keywords:
SARS-CoV-2headachemigrainepost-COVID-19

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