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Updated: Oct 25, 2025

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
Device interaction between cardiac contractility modulation (CCM) and subcutaneous defibrillator (S-ICD).
Luca Trolese1, Thomas Faber1, Alexander Gressler1
1Department of Cardiology and Angiology I, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Combined cardiac contractility modulation (CCM) and subcutaneous implantable cardioverter-defibrillator (S-ICD) is safe. Reprogramming resolved S-ICD interference, improving heart failure symptoms in a patient.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Devices
Background:
- Cardiac contractility modulation (CCM) and subcutaneous implantable cardioverter-defibrillators (S-ICDs) are advanced therapies for heart conditions.
- Combined implantation aims to reduce lead-related complications and improve patient outcomes.
Observation:
- A patient with ischemic cardiomyopathy received a CCM device alongside an existing S-ICD.
- Post-implantation crosstalk testing revealed S-ICD misinterpretation of cardiac signals (QRS and T waves).
Findings:
- Device interference was successfully resolved by reprogramming the CCM device.
- The S-ICD maintained its therapeutic functionality without compromise.
- The patient experienced improved heart failure symptoms post-intervention.
Implications:
- Combined CCM and S-ICD therapy is a potentially safe and effective strategy for managing heart failure and arrhythmias.
- Careful device programming and crosstalk assessment are crucial for successful co-implantation.
- This approach may offer a lead-sparing alternative for select patient populations.
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