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Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
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Cervicofacial actinomycosis: a unique diagnostic challenge.
Lisa Fronek1, Brett Brazen, Risa Ross
1Department of Dermatology, HCA Healthcare/University of South Florida Morsani College of Medicine, Largo, FL. drlisafronek@gmail.com.
Dermatology Online Journal
|August 15, 2021
Summary
Actinomycosis, a rare bacterial infection, can affect the face and jaw. This case highlights diagnosis and treatment in a patient without typical risk factors like dental issues.
Area of Science:
- Infectious Diseases
- Oral and Maxillofacial Surgery
- Bacteriology
Background:
- Actinomycosis is a chronic bacterial infection caused by *Actinomyces israelii*, an anaerobic, gram-positive bacterium.
- It commonly colonizes the oral, digestive, and genital tracts, with cervicofacial actinomycosis affecting the mandible in 50% of cases.
- Typically, infections occur in immunocompetent individuals with mucosal trauma from dental procedures or poor hygiene.
Observation:
- This report details a 54-year-old male diagnosed with cervicofacial actinomycosis.
- The patient presented with infection in the absence of periodontal disease or recent dental procedures, challenging typical etiological assumptions.
- The case underscores the importance of considering actinomycosis even without common predisposing factors.
Findings:
- The study discusses the pathogenesis, clinical presentation, and histological findings of actinomycosis.
- Diagnostic techniques, including imaging and microbiological analysis, are reviewed.
- Current treatment strategies for actinomycosis are explored, emphasizing timely intervention.
Implications:
- Accurate and prompt recognition of actinomycosis is crucial for effective management.
- This case and review aim to guide physicians across specialties in diagnosing and treating cervicofacial actinomycosis.
- Understanding atypical presentations can improve patient outcomes for this rare infection.
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