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Cervical Recurrence from an Intraparotid Kimura Disease
L Esparza Lasaga1,2, R Bemúdez Cameo3, A Valero Torres3
1Oral and Maxillofacial Department, Miguel Servet University Hospital, Isabel la Católica 1-3, 50009 Zaragoza, Spain.
Journal of Maxillofacial and Oral Surgery
|August 19, 2021
Summary
Kimura disease is a rare lymphoproliferative disorder affecting skin and lymph nodes, primarily in Asian males. Early consideration of this condition is crucial for effective management and diagnosis.
Area of Science:
- Immunology
- Oncology
- Dermatology
Background:
- Kimura disease is a rare, benign, chronic, lymphoproliferative disorder of unknown etiology.
- It primarily affects the skin and lymph nodes, predominantly observed in males from Asia.
Observation:
- A 55-year-old man presented with neck and intraparotid lymphadenopathy.
- Surgical removal and histological examination confirmed Kimura disease.
Findings:
- Kimura disease is characterized by lymphocyte follicular hyperplasia, eosinophilic infiltration, fibrocollagenous deposition, and vascular proliferation.
- While endemic in the Far East, it is exceptional in Europe, with fewer than 200 reported cases globally, and less than 40 involving the parotid region.
Implications:
- Kimura disease should be considered in patients with cervical masses, especially those of East Asian descent, presenting with hypereosinophilia or elevated IgE levels.
- Surgical intervention is the primary treatment, though recurrence is common, highlighting the need for ongoing monitoring and research into alternative therapies.
