Multimodal Imaging Findings in Two Children With Microphthalmos

Area of Science:

• Ophthalmology
• Medical Genetics
• Developmental Biology

Background:

• Microphthalmos (microphthalmia) is a rare congenital eye disorder.
• It results from genetic, chromosomal, or environmental factors.
• Clinical presentations range from nanophthalmia to posterior microphthalmia.

Purpose of the Study:

• To review the clinical and imaging findings of microphthalmos.
• To consolidate existing literature on this rare condition.

Main Methods:

• Literature review of clinical presentations.
• Analysis of imaging modalities in microphthalmos cases.

Main Results:

• Microphthalmos affects approximately 1 in 1,000 individuals.
• There is limited literature on detailed clinical and imaging findings.

Conclusions:

• Microphthalmos is a complex developmental disorder with varied presentations.
• More research is required to fully understand its clinical spectrum and diagnostic imaging characteristics.