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Clinical Characteristics and Outcomes of Hypertensive Patients Infected with COVID-19: A Retrospective Study

Liqin Chen1, Jiankun Chen1,2, Yuwan Wu1

  • 1The Second Affiliated Hospital (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, People's Republic of China.

International Journal of General Medicine
|August 25, 2021
PubMed

Insights

Hypertension is common in COVID-19 patients and associated with more severe disease. Managing hypertension and other conditions is crucial for better COVID-19 outcomes.

Area of Science:

  • Medical research
  • Infectious diseases
  • Cardiology

Background:

  • Hypertension is the most common comorbidity in COVID-19 patients.
  • Understanding clinical differences is vital for patient management.

Purpose of the Study:

  • Compare clinical characteristics and outcomes of COVID-19 patients with and without hypertension.
  • Investigate the impact of hypertension on COVID-19 severity.

Main Methods:

  • Retrospective analysis of 944 hospitalized COVID-19 patients (January-March 2020).
  • Extracted data included clinical features, lab results, complications, treatments, and outcomes.
  • Compared patient groups based on hypertension status.

Main Results:

  • 32.94% of COVID-19 patients had hypertension.
  • Hypertensive COVID-19 patients showed higher rates of type 2 diabetes, coronary heart disease, chronic kidney disease, and poststroke syndrome.
  • Elevated inflammatory markers (ESR, CRP, SAA) and blood glucose levels were observed in hypertensive patients.
  • Higher incidence of pleural effusion on CT scans in hypertensive COVID-19 patients.

Conclusions:

  • Hypertension frequently coexists with other conditions in COVID-19 patients, potentially worsening disease severity.
  • Effective management of hypertension and comorbidities is essential for improving clinical outcomes in COVID-19.
Abstract

Keywords:
COVID-19clinical characteristicscomorbiditiescoronavirus diseasehypertension

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