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The Association between Breastfeeding Duration and Lipid Profile among Children and Adolescents
1Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing 100191, China.
Insights
Prolonged breastfeeding is linked to lower cholesterol levels in children and adolescents. Extended breastfeeding duration, especially over 12 months, significantly reduces total cholesterol and the risk of abnormal lipid profiles.
Area of Science:
- Pediatric Nutrition
- Cardiovascular Health
- Public Health
Background:
- Childhood lipid profiles are critical indicators of future cardiovascular health.
- Understanding modifiable factors influencing pediatric lipid metabolism is essential for early intervention.
- Breastfeeding is a key nutritional practice with potential long-term health implications.
Purpose of the Study:
- To examine the association between the duration of breastfeeding and the lipid profiles of children and adolescents.
- To determine if prolonged breastfeeding influences levels of total cholesterol, LDL-C, HDL-C, and TC/HDL-C.
- To assess the impact of breastfeeding duration on the risk of abnormal lipid profiles in young populations.
Main Methods:
- A cross-sectional survey involving a national sample of 12,110 Chinese children and adolescents aged 5-19 years.
- Data collection included questionnaires for breastfeeding duration and sociodemographic factors.
- Linear and logistic regression models were used to analyze the relationship between breastfeeding duration and lipid profiles.
Main Results:
- Prolonged breastfeeding (over 12 months) was significantly associated with lower levels of total cholesterol (TC), LDL-C, HDL-C, and TC/HDL-C.
- Participants breastfed for over 12 months showed reduced levels of TC, LDL-C, HDL-C, and TC/HDL-C compared to non-breastfed children.
- The risk of high TC decreased by 43% in children breastfed for over 12 months, with the association being more pronounced in younger age groups (5-14 years).
Conclusions:
- Extended breastfeeding duration is positively associated with favorable lipid profiles in children and adolescents.
- Prompting prolonged breastfeeding may be an effective public health strategy to improve childhood lipid profiles and reduce cardiovascular risk.
- The beneficial effects of prolonged breastfeeding on lipid profiles are particularly evident in younger children and adolescents.
Abstract:
To investigate the relationship between breastfeeding duration and lipid profile among children and adolescents, a cross-sectional survey using random cluster sampling was performed, and a national sample of 12,110 Chinese children and adolescents aged 5-19 years were collected. Breastfeeding duration and sociodemographic factors were collected by questionnaires. Fasting blood samples were obtained to test the lipid profile. Linear regression and logistic regression models were employed to evaluate the association between breastfeeding duration and lipid profile. We found that prolonged breastfeeding was related with a low level of total cholesterol (TC), LDL-C, HDL-C, and TC/HDL-C in children and adolescents. With an increased duration of breastfeeding, the magnitude of the association between breastfeeding and lipid profile enlarged. The levels of TC, LDL-C, HDL-C, and TC/HDL-C in participants who were breastfed for more than 12 months decreased by 6.225 (95% CI: -8.390, -4.059), 1.956 (95% CI: -3.709, -0.204), 1.273 (95% CI: -2.106, -0.440) mg/dL, and 0.072 (95%CI: -0.129, -0.015), respectively, compared with those who were not breastfed. The corresponding risk of high TC declined by 43% (aOR: 0.570, 95% CI: 0.403, 0.808). The association was similar in both boys and girls, but only statistically significant in children and young adolescents aged 5-14 years. This suggested that prolonged breastfeeding duration was related with low lipid levels and decreased abnormal lipid risk, especially in children and young adolescents. These findings support the intervention of prompting a prolonged duration of breastfeeding to improve the childhood lipid profile.
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