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Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
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Shunting outcomes in communicating hydrocephalus: protocol for a multicentre, open-label, randomised controlled trial
Tong Sun1, Wenyao Cui1, Jingguo Yang1
1Department of Neurosurgery, Sichuan University West China Hospital, Chengdu, Sichuan, China.
BMJ Open
|August 27, 2021
Summary
This study compares lumboperitoneal shunt (LPS) and ventriculoperitoneal shunt (VPS) for communicating hydrocephalus. It will determine the effectiveness and safety of LPS versus VPS in treating this condition.
Area of Science:
- Neurosurgery
- Medical Devices
- Clinical Trials
Background:
- Ventriculoperitoneal shunt (VPS) is the standard treatment for communicating hydrocephalus.
- Lumboperitoneal shunt (LPS) is emerging as an alternative, but evidence comparing the two is limited.
- High-quality comparative studies are needed to guide clinical practice.
Purpose of the Study:
- To compare the effectiveness and safety of LPS versus VPS in patients with communicating hydrocephalus.
- To evaluate shunt failure rates and clinical outcomes over a 2-year follow-up period.
- To assess secondary outcomes including neurological scales, imaging, and cost-effectiveness.
Main Methods:
- Randomized controlled trial comparing LPS and VPS in a 1:1 ratio.
- Inclusion of adult patients (18-90 years) with communicating hydrocephalus.
- Primary outcome: shunt failure rate at 2 years; secondary outcomes: clinical scales, safety, and cost-effectiveness.
Main Results:
- This section is to be filled after study completion.
Conclusions:
- This section is to be filled after study completion.
