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Congenital infection with herpes simplex virus type 1
1Department of Dermatology, Hospital for Sick Children, London.
Pediatric Dermatology
|December 1, 1987
Summary
Congenital herpes simplex virus (HSV) type 1 infection in newborns can cause extensive skin lesions. Early diagnosis and intravenous acyclovir treatment led to a full recovery with no long-term complications in this case.
Area of Science:
- Neonatal Medicine
- Virology
- Dermatology
Background:
- Congenital herpes simplex virus (HSV) infection is a rare but serious condition in newborns.
- Early diagnosis and treatment are crucial to prevent severe outcomes such as mortality and long-term disability.
Observation:
- A newborn presented with extensive skin lesions indicative of congenital HSV type 1 infection.
- Diagnosis was delayed until the fifth day of life.
- No other organs were involved at the time of presentation.
Findings:
- Intravenous acyclovir treatment was initiated.
- The infant experienced a complete recovery.
- At 18 months of age, the child exhibited no neurological or ophthalmological abnormalities.
Implications:
- This case highlights the importance of recognizing congenital HSV infection in neonates, even with seemingly isolated skin manifestations.
- Pediatricians and dermatologists should maintain a high index of suspicion for HSV in neonates presenting with skin lesions.
- Prompt diagnosis and treatment with antiviral therapy can significantly improve outcomes and prevent severe handicaps.