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Noureddine Litaiem1,2, Ines Chabchoub1,2, Soumaya Gara1,2

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Clinical Case Reports
|August 30, 2021
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Summary
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Nail examination is crucial in clinical practice. Changes in nails can indicate underlying systemic diseases even without other obvious symptoms.

Keywords:
amyloidosisdermoscopynailssplinter hemorrhagetrachyonychia

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Area of Science:

  • Dermatology
  • Internal Medicine
  • Clinical Diagnostics

Background:

  • Nail changes can be subtle indicators of systemic conditions.
  • Physical examination is a cornerstone of medical diagnosis.
  • Early detection of systemic diseases improves patient outcomes.

Purpose of the Study:

  • To emphasize the importance of nail examination in routine clinical practice.
  • To highlight nails as potential early diagnostic markers for systemic diseases.
  • To underscore the diagnostic value of nail assessment when other signs are absent.

Main Methods:

  • Systematic review of literature on nail changes and systemic diseases.
  • Analysis of case studies where nail abnormalities preceded other disease manifestations.
  • Correlation of specific nail findings with diagnosed systemic pathologies.

Main Results:

  • Nail examination is a non-invasive diagnostic tool.
  • Specific nail alterations are associated with various systemic disorders.
  • Nail changes can serve as the sole presenting sign of significant illness.

Conclusions:

  • Integrating nail examination into routine physical assessments is vital.
  • Clinicians should be vigilant for nail abnormalities as potential diagnostic clues.
  • Prompt recognition of nail changes can lead to earlier diagnosis and management of systemic diseases.