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Related Experiment Videos

Avian thyroid isthmus.

T R Scott1, B Glick, G T Pharr

  • 1Poultry Science Department, Mississippi State University, Mississippi State 39762.

Poultry Science
|November 1, 1987
PubMed
Summary
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Thiouracil treatment in chickens induced an avian thyroid isthmus, a structure previously only seen in mammals. Histological analysis confirmed this connecting tissue shares cellular composition with the thyroid glands.

Area of Science:

  • Comparative anatomy
  • Endocrinology
  • Avian biology

Background:

  • The thyroid isthmus, a connecting tissue between thyroid lobes, is well-documented in mammals.
  • Its presence in avian species has not been previously established.

Purpose of the Study:

  • To investigate the potential for an avian thyroid isthmus formation.
  • To characterize the histological properties of any observed connecting thyroid tissue in chickens.

Main Methods:

  • Two experiments were conducted using chickens from hatching to 6 and 8 weeks of age.
  • A diet supplemented with 0.1% thiouracil was administered.
  • Thyroid tissues were examined histologically.

Main Results:

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  • Thiouracil treatment resulted in the appearance of thyroid tissue connecting the thyroid glands in chickens.
  • Histological examination confirmed the connecting tissue was composed of the same cell types as the thyroid glands, indicating an avian thyroid isthmus.

    • Conclusions:

    • An avian equivalent of the mammalian thyroid isthmus can be experimentally induced.
    • Thiouracil is implicated in the formation of this anatomical structure in chickens.